Charcot-Marie-Tooth disease

It is the hereditary disorder which infect the nerves of legs and arms. It is also called hereditary motor and sensory neuropathy. In this disease mostly peripheral nerves are affected.

Symptoms

Below mention are the signs and symptoms of Charcot-Marie-tooth disease:

High foot arches
Curled toes
Weakness in legs
Difficulty to lift foot
Falling
Decrease sensation
Foot drop

Causes

It is occurred due to the inherited mutation in the genes which form the myeline sheath around the nerves. Mutation cause error in the formation of myelin sheath. Sometimes mutation also affect the nerves.

Diagnosis

Diagnosis can be made by:

Physical examination to check any physical abnormality.
Check the reflexes and muscles strength
Nerve conduction test
Check the gait of patient
Check sensation over the feet and hands
EEG to check electrical activity of brain
Genetic testing

Treatment

Treatment options include:

To reduce the muscle stiffness and pain.
Physical therapy to strength the muscle and tightening the muscles.
Orthopedic devices to prevent injury.
Surgery to correct the foot surgery and improves weakness

Charcot-Marie-Tooth disease