It is defined as the continuous feeling of sadness and lack of interest in daily routine work. It is a mood disorder which affects your thinking, physical and emotional abilities. It is also called clinical depression.


Signs and symptoms of depression include:Depression SYMPTOMS CAUSES TREATMENT

  • Lack of interest in daily routine work
  • Angry on little things
  • Sleep issues
  • Feeling sad and hopeless
  • Reduce appetite
  • Anxiety
  • Frustration
  • Slow thinking process
  • Suicidal thoughts

As like other brain disorder depression is also a multi-factorial disease which is occur due to many factors which involved:

  • Hormones change the body’s internal environment and may involve in the mood swings like depression occur after delivery or menopause or in thyroid gland diseases.
  • Neurotransmitter which are called brain chemicals also involved in depression.
  • Biological changes in brain physical structure also increase the risk of depression
  • It is also run in families as inherited traits

Diagnostic tests include:

  • Blood test to check the complete blood count
  • Hormonal test to check the level of certain hormones
  • DSM-5 criteria to diagnose the stage of depression
  • Physical test

Treatment option include medications and psychotherapy.


  • Serotonin-norepinephrine reuptake inhibitors like venlafaxine and duloxetine.
  • Selective-serotonin reuptake inhibitors like citalopram and fluoxetine
  • Tricyclic antidepressants like nefazodone and mirtazapine
  • Monoamine oxidase inhibitors like phenelzine and tranylcypromine

Psychotherapy involved a session with your doctor to whom you tell about feelings and thoughts and your psychiatrist will help you to find the solution of your problems and decrease negativity from your life. It includes different types of therapy depend upon the cause of your depression

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